An antibody-modified atomic force microscope tip was used to detect conformational changes of fibronectin deposited on a poly(methyl methacrylate)/poly(acrylic acid) block copolymer compared to PMMA and a random poly(methyl methacrylate)/poly(acrylic acid) copolymer with an identical chemical composition.
04 January 2012
Members' Content
Bio-sensing represents one of the most attractive applications of carbon material based electronic devices; nevertheless, the complete integration of bioactive transducing elements still represents a major challenge, particularly in terms of preserving biological function and specificity while maintaining the sensor's electronic performance.
23 August 2011
The absence of an optimal nano-sized reference material has been the biggest obstacle in evaluating the safety of carbon nanotubes as biomaterials.
23 August 2011
Biosensing is paramount for improving the quality of human life. Biosensors and biosensing protocols are able to detect a wide range of compounds, sensitively and selectively, with applications in security, health care for point-of-care analyses of diseases, and environmental safety.
08 July 2011
Carbon nanotubes and graphene are both low-dimensional sp2 carbon nanomaterials exhibiting many unique physical and chemical properties that are interesting in a wide range of areas including nanomedicine.
08 July 2011
Nanotechnology has given scientists new tools for the development of advanced materials for the detection and diagnosis of disease. In particular, superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents due to a combination of favorable superparamagnetic properties, biodegradability, and surface properties.
08 July 2011
The preservation of waterlogged archaeological wooden finds, such as Henry VIII's flagship the Mary Rose, is complicated by the biological, chemical, and mechanical changes induced from prolonged exposure to a marine environment. Of particular concern are sulfur species that form acidic compounds that attack wood. Here we show that different sulfur compounds do not form acids at the same rate or pathway and propose a preservation strategy of applying SrCO3 nanoparticles.
08 July 2011
We examine several systems where protein hot spots, the active domains on proteins and the interactive dynamics in them, play a critical role in the interactions at the interface of these unique systems.
08 July 2011
The fruit fly Drosophila melanogaster is a versatile model organism that has been used in biomedical research for over a century to study a broad range of phenomena. There are many technical advantages of using Drosophila over vertebrate models; they are easy and inexpensive to culture in laboratory conditions, have a much shorter life cycle, they produce large numbers of externally laid embryos and they can be genetically modified in numerous ways.
16 May 2011
Due to the limited ability of the adult lung to regenerate and the frequency of lung disease, the lung is a tissue that can especially benefit from regenerative medicine. Prospects for lung regeneration have made great strides in the past year. In this review, we summarize recent progress and key challenges for approaches in lung regenerative medicine.
16 May 2011