In recent years, considerable progress has been achieved in the study of nuclear reactions at intermediate and high energies involving the disintegration of the colliding nuclei. Isotopic effects observed in collisions of nuclei with large asymmetry have been employed to obtain information on the equation of state of isospin-asymmetric matter in the laboratory, thereby complementing astrophysical observations. The formation of hyper-fragments in high-energy nuclear collisions has improved our understanding of hyperon-nuclear interactions, thus extending the study of nuclear matter into the strangeness sector.

The knowledge accumulated in these fields, while presently being far from complete, is needed for a realistic description of nuclear matter under extreme astrophysical conditions, as for example in supernova explosions and neutron stars. At the same time, nuclear fragmentation reactions appear to be important in many practical applications. They include the use of proton and ion beams for cancer therapy, transmutation of radioactive waste, new accelerator-driven methods of energy production, and protection of space missions against cosmic radiation.

The aim of this conference is bringing together leading experts and active scientists from different fields, to summarize the present status of research and discuss future developments, to strengthen the cooperation between the groups, and to exchange ideas and experience. The site and the schedule of the conference will provide excellent possibilities for informal communication between participants and for establishing new collaborations. 

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