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The content or purity of the main component of a sample is often of interest in research, development, and quality control laboratories. Purity analysis allows you to check the purity and identity of a substance. The method requires only a few milligram of a sample. You quickly obtain purity results with an accuracy of typically 10% of the impurity. In addition, the evaluation allows you to calculate the melting point of the pure substance.

Differential Scanning Calorimetry (DSC) is the most widely used thermal analysis technique. A well-established application is the purity determination of organic substances. The method is based on the van’t Hoff law of melting point depression of eutectic systems. Purities between 90 and 100 mol% can be reliably determined. Purity determination is used in the chemical and pharmaceutical industries and also for additives in the food and plastics industries.

The presentation covers the following topics:

  • Basic principles
  • Why use DSC Purity Determination?
  • Industries and applications
  • Application examples

In this presentation, we will discuss the basic principles of DSC purity determination and present some interesting applications.

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