Polymer multi-layer films are used in a variety of industries. In food packaging, for example, polymer laminates are used not only to protect the food, but also to retain aroma and flavors, and to extend shelf life. Multi-layer films are produced using co-extrusion and lamination techniques. Some of the problems that can occur during film manufacture include the introduction of defect particles and separation of the layers. Current analytical methods used to examine the materials during and after production include NMR, DSC and FT-IR. Vibrational spectroscopy is a valuable addition to these techniques because it provides definitive molecular information. Raman spectroscopy is complementary to FT-IR and offers advantages that include higher spatial resolution and easier sample preparation.