The drive to develop bone grafts for the filling of major gaps in the skeletal structure has led to a major research thrust towards developing biomaterials for bone engineering. Unfortunately, from a clinical perspective, the promise of bone tissue engineering which was so vibrant a decade ago has so far failed to deliver the anticipated results of becoming a routine therapeutic application in reconstructive surgery. Here we describe the analysis of long-term bone regeneration studies in preclinical animal models, exploiting methods of micro- and nano analysis of biodegradable composite scaffolds.
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Materials Today (2012) 15(10), 430-434
Banner image reproduced from "Osteophilic Multilayer Coatings for Accelerated Bone Tissue Growth" by Nisarg J. Shah , Jinkee Hong , Md. Nasim Hyder , and Paula T. Hammond, Adv. Mater. (2012) DOI: 10.1002/adma.201104475.