The design and synthesis of molecularly or supra-molecularly defined interfacial architectures have seen in recent years a remarkable growth of interest and scientific research activities for various reasons. On the one hand it is generally believed that the construction of an interactive interface between the living world of cells, tissue or whole organisms and the (inorganic or organic) materials world of technical devices, like implants or medical parts requires the proper construction and structural (and functional) control of this organism-machine interface.