Recent developments in oblique angle deposition and other nanofabrication techniques have overcome this limitation, providing an unprecedented opportunity to develop SERS substrates for pathogen biosensor applications. Recently reported examples of SERS's newfound sensing abilities include the capacity to detect low levels of viruses and bacteria, as well as to discriminate between types and strains of pathogens, including pathogens with gene deletions. A brief review of our recent progress in SERS biosensing is given in this article.


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