While crystals have been studied for centuries and are ubiquitous in daily life – they are in our bones, the food we eat and the batteries we use – scientists still don't fully understand how crystals grow or how to efficiently manufacture them. As a consequence, scientific efforts to improve a wide range of crystalline materials, from self-healing biomaterials to solar panels, have been limited.
Researchers at the University of Illinois at Chicago (UIC) have now unlocked part of this mystery. By using computer-based simulations to analyze how atoms and molecules move in a solution, the UIC team has identified a general mechanism governing crystal growth that scientists can manipulate when developing new materials.
Specifically, the researchers found that when crystal-forming molecules are surrounded by a solvent, like water, the solvent molecules form a shield that they call a solvation shell. When this shield fluctuates, the crystal-forming molecules can break free to form crystals. The researchers also showed that temperature, solvent type and the number of solvent molecules all affect the shell's fluctuation, as they report in a paper in the Proceedings of the National Academy of Sciences.
"For the first time, we have shown what happens when a molecule leaves a solvent to form a crystal," said Meenesh Singh, senior author and assistant professor of chemical engineering at the UIC College of Engineering. "Under the right conditions, the shield 'dances' around and allows molecules to break free and integrate into the crystal surface. The fluctuations in the solvation shell are key molecular events that explain how crystals form – knowledge of this mechanism has been missing since the inception of crystallization research."
Understanding this mechanism will provide scientists with greater ability to direct molecules to form crystals with specific structures, shapes and sizes. "This will allow us to make better materials for a wide class of products used in daily life," Singh said. Examples include bone implants to promote biomineralization, better drug delivery systems, more stable lithium batteries, and improved semiconductors and agricultural chemicals.
"The molecular insight gained from this study will also help save money in various chemical industries by reducing the need for hit or miss techniques in thousands of trials," said UIC graduate student Anish Dighe, co-author of the paper. "With the help of this study, we can now design systems that can crystallize the desired solute molecule without so many trials."
This story is adapted from material from the University of Illinois at Chicago, with editorial changes made by Materials Today. The views expressed in this article do not necessarily represent those of Elsevier. Link to original source.
This illustration shows how local fluctuations allow molecules to leave the solvation shell and integrate into the crystal surface. Image: Meenesh Singh.