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This week Dr. Zhen Gu from North Carolina State University and the University of North Carolina at Chapel Hill spoke to Stewart Bland about targeted drug delivery.
Researchers have developed a technique for creating nanoparticles that carry two different cancer-killing drugs into the body and deliver those drugs to separate parts of the cancer cell where they will be most effective. Gu’s research team developed nanoparticles with an outer shell made of hyaluronic acid (HA) woven together with TRAIL. The HA interacts with receptors on cancer cell membranes, which “grab” the nanoparticle. Enzymes in the cancer cell environment break down the HA, releasing TRAIL onto the cell membrane and ultimately triggering cell death.
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There is a pressing need for nano education in formal and informal settings.
Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy.
Find out more about the Biomaterials Outstanding Paper Award and submit your nomination.
Explore the first issue of HardwareX.
Advances in polymerization have enabled their use in cosmetics, drugs, biomedical devices, paints, coatings, adhesives, and microelectronics
Elsevier Editors claimed awards at Society for Biomaterials 2017 Annual Meeting.