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This week Dr. Zhen Gu from North Carolina State University and the University of North Carolina at Chapel Hill spoke to Stewart Bland about targeted drug delivery.
Researchers have developed a technique for creating nanoparticles that carry two different cancer-killing drugs into the body and deliver those drugs to separate parts of the cancer cell where they will be most effective. Gu’s research team developed nanoparticles with an outer shell made of hyaluronic acid (HA) woven together with TRAIL. The HA interacts with receptors on cancer cell membranes, which “grab” the nanoparticle. Enzymes in the cancer cell environment break down the HA, releasing TRAIL onto the cell membrane and ultimately triggering cell death.
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Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy.
There is a pressing need for nano education in formal and informal settings.
Water-based, biocompatible ink formulations of two-dimensional materials including graphene, MoS2, WS2, and hexagonal boron nitride.
Nanostructured scaffold material impregnated with immunosuppressive drugs encourages nerve regrowth in implanted replacement teeth.
Materials Today Interview with Dr Davide Crivelli from the Politecnico di Milano about acoustic emission.
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