Biointeractive hydrogels

Poly(ethylene glycol), or PEG, is used extensively in biomedical device development, with applications in tissue engineering, ultrahigh-density protein chips, and in vitro microdevices. We highlight some of the many recent advances in PEG hydrogel technology that center on chemical modifications to impart biospecificity and patterning to control structure on micro- and nanoscales characteristic of individual cells and proteins.