Calcium phosphate cements and putties

Acta Biomaterialia is proud to announce the journals first virtual special issue, examining the applications of calcium phosphate cements and putties.

Introducing the issue is Editor Marc Bohner, PhD, Head of the Skeletal Substitutes Group, RMS Foundation, Switzerland:

When I started my PhD thesis on calcium phosphate cements just 24 years ago, it was very difficult to find articles related to the topic. This was only partly because the field was new; mainly it was because there was no widespread internet as there is now. Searching for an article required painstaking effort: go to the library, look through books and microfilm databases, identify the physical location of the article, find it or order it, and finally copy it. Obviously, over time this process has changed dramatically, as now articles are only a few mouse clicks away. However, finding articles still remains a problem. Now the problem is the time it takes to process so much information received every day. With this in mind,  we offer our first “virtual issue” for researchers to find within a few seconds some of the most interesting work on the same topic in one place, in this case, on the topic of Calcium Phosphate Cements as biomaterials.

Calcium phosphates are among the most attractive materials for bone graft substitution due to their chemical similarity to bone mineral and their excellent biological response. However, their handling and biological performance could still be improved.

In the first Acta Biomaterialia virtual issue, the 24 articles presented on this particular topic are at the forefront of what can be done with calcium phosphate cements and putties, and we hope this issue might stimulate further research and advancement towards improving production methods and applications for this field of materials.

We welcome your new submissions to Acta Biomaterialia on this topic.

Papers included in this virtual special issue:

• Barbieri D, Yuan H, Luo X, Farè S, Grijpma DW, De Bruijn JD. Influence of polymer molecular weight in osteoinductive composites for bone tissue regeneration. Acta Biomaterialia. 2013;9:9401-13.

• Butscher A, Bohner M, Doebelin N, Galea L, Loeffel O, Müller R. Moisture based three-dimensional printing of calcium phosphate structures for scaffold engineering. Acta Biomaterialia. 2013;9:5369-78.

• Butscher A, Bohner M, Doebelin N, Hofmann S, Müller R. New depowdering-friendly designs for three-dimensional printing of calcium phosphate bone substitutes. Acta Biomaterialia. 2013;9:9149-58.

• Canal C, Pastorino D, Mestres G, Schuler P, Ginebra MP. Relevance of microstructure for the early antibiotic release of fresh and pre-set calcium phosphate cements. Acta Biomaterialia. 2013;9:8403-12.

• Despas C, Schnitzler V, Janvier P, Fayon F, Massiot D, Bouler JM, et al. High-frequency impedance measurement as a relevant tool for monitoring the apatitic cement setting reaction. Acta Biomaterialia. 2013.

• D'Este M, Eglin D. Hydrogels in calcium phosphate moldable and injectable bone substitutes: Sticky excipients or advanced 3-D carriers? Acta Biomaterialia. 2013;9:5421-30.

• Heinemann S, Rössler S, Lemm M, Ruhnow M, Nies B. Properties of injectable ready-to-use calcium phosphate cement based on water-immiscible liquid. Acta Biomaterialia. 2013;9:6199-207.

• Kutikov AB, Song J. An amphiphilic degradable polymer/hydroxyapatite composite with enhanced handling characteristics promotes osteogenic gene expression in bone marrow stromal cells. Acta Biomaterialia. 2013;9:8354-64.

• Liu W, Zhang J, Weiss P, Tancret F, Bouler JM. The influence of different cellulose ethers on both the handling and mechanical properties of calcium phosphate cements for bone substitution. Acta Biomaterialia. 2013;9:5740-50.

• Montufar EB, Maazouz Y, Ginebra MP. Relevance of the setting reaction to the injectability of tricalcium phosphate pastes. Acta Biomaterialia. 2013;9:6188-98.

• Renno ACM, Van De Watering FCJ, Nejadnik MR, Crovace MC, Zanotto ED, Wolke JGC, et al. Incorporation of bioactive glass in calcium phosphate cement: An evaluation. Acta Biomaterialia. 2013;9:5728-39.

• Samavedi S, Whittington AR, Goldstein AS. Calcium phosphate ceramics in bone tissue engineering: A review of properties and their influence on cell behavior. Acta Biomaterialia. 2013;9:8037-45.

• Schumache M, Henß A, Rohnke M, Gelinsky M. A novel and easy-to-prepare strontium(II) modified calcium phosphate bone cement with enhanced mechanical properties. Acta Biomaterialia. 2013;9:7536-44.

• Schumacher M, Lode A, Helth A, Gelinsky M. A novel strontium(II)-modified calcium phosphate bone cement stimulates human-bone-marrow-derived mesenchymal stem cell proliferation and osteogenic differentiation in vitro. Acta Biomaterialia. 2013;9:9547-57.

• Vorndran E, Geffers M, Ewald A, Lemm M, Nies B, Gbureck U. Ready-to-use injectable calcium phosphate bone cement paste as drug carrier. Acta Biomaterialia. 2013;9:9558-67.

• Zhang J, Liu W, Schnitzler V, Tancret F, Bouler JM. Calcium phosphate cements for bone substitution: Chemistry, handling and mechanical properties. Acta Biomaterialia. 2013.

• Bleek K, Taubert A. New developments in polymer-controlled, bioinspired calcium phosphate mineralization from aqueous solution. Acta Biomaterialia. 2013;9:6283-321.

• Bongio M, Van Den Beucken JJJ, Nejadnik MR, Tahmasebi Birgani Z, Habibovic P, Kinard LA, et al. Subcutaneous tissue response and osteogenic performance of calcium phosphate nanoparticle-enriched hydrogels in the tibial medullary cavity of guinea pigs. Acta Biomaterialia. 2013;9:5464-74.

• Hayakawa S, Kanaya T, Tsuru K, Shirosaki Y, Osaka A, Fujii E, et al. Heterogeneous structure and in vitro degradation behavior of wet-chemically derived nanocrystalline silicon-containing hydroxyapatite particles. Acta Biomaterialia. 2013;9:4856-67.

• Hoekstra JWM, Ma J, Plachokova AS, Bronkhorst EM, Bohner M, Pan J, et al. The in vivo performance of CaP/PLGA composites with varied PLGA microsphere sizes and inorganic compositions. Acta Biomaterialia. 2013;9:7518-26.

• Sadat-Shojai M, Khorasani MT, Dinpanah-Khoshdargi E, Jamshidi A. Synthesis methods for nanosized hydroxyapatite with diverse structures. Acta Biomaterialia. 2013.

• Suzuki K, Anada T, Miyazaki T, Miyatake N, Honda Y, Kishimoto KN, et al. Effect of addition of hyaluronic acids on the osteoconductivity and biodegradability of synthetic octacalcium phosphate. Acta Biomaterialia. 2014;10:531-43.

• Tadier S, Galea L, Charbonnier B, Baroud G, Bohner M. Phase and size separations occurring during the injection of model pastes composed of β-tricalcium phosphate powder, glass beads and aqueous solutions. Acta Biomaterialia. 2014.

• Wang H, Bongio M, Farbod K, Nijhuis AWG, Van Den Beucken J, Boerman OC, et al. Development of injectable organic/inorganic colloidal composite gels made of self-assembling gelatin nanospheres and calcium phosphate nanocrystals. Acta Biomaterialia. 2014;10:508-19.